SIYDIK YO‘LLARI INFEKSIYALARIDA ANTIBIOTIK REZISTENTLIGI MUAMMOSI
Keywords:
siydik yo‘llari infeksiyasi, antibiotik rezistentligi, Escherichia coli, ESBL, antimikrob terapiya, farmakologik monitoring.Abstract
Siydik yo‘llari infeksiyalari (SYI) dunyo bo‘yicha eng keng tarqalgan bakterial infeksiyalardan biri hisoblanadi va ularning davolanishida antibiotiklarga rezistentlik muammosi tobora dolzarblashib bormoqda. Mazkur maqolada SYI etiologiyasi, asosiy patogenlar, antibiotiklarga chidamlilik mexanizmlari hamda zamonaviy epidemiologik ko‘rsatkichlar ilmiy manbalar asosida tahlil qilindi. So‘nggi yillarda, ayniqsa, Escherichia coli shtammlarida keng spektrli beta-laktamazalar (ESBL) ishlab chiqarish darajasi oshib borayotgani qayd etilgan. Tadqiqot natijalari antibiotiklarni oqilona qo‘llash, mikrobiologik monitoringni kuchaytirish va mahalliy rezistentlik xaritalarini ishlab chiqish zarurligini ko‘rsatadi.
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